DMARDs Latest Treatment Option for Rheumatoid Arthritis

by Dr. Naseem Arshad

July 22, 2024

Rheumatoid arthritis treatment has advanced significantly in recent years. One of the most important developments is the arrival of Biologic DMARDs — a new class of medicines developed after extensive research and now readily available in Pakistan. To understand where they fit in, it helps to understand what DMARDs are.

What are DMARDs?

DMARDs stands for Disease-Modifying Anti-Rheumatic Drugs. Unlike simple painkillers, which only reduce symptoms, DMARDs act on the disease process itself. They slow down the overactive immune response that drives rheumatoid arthritis, controlling inflammation and preventing long-term joint damage. This is why DMARDs are considered the foundation of rheumatoid arthritis treatment.

Conventional DMARDs

For most patients, treatment begins with conventional DMARDs such as methotrexate. These medicines are well established, effective, and suitable for the majority of people with rheumatoid arthritis. Taken regularly and monitored properly, they can bring the disease under good control and keep patients active.

Biologic DMARDs — the latest option

When conventional DMARDs do not control the disease well enough, Biologic DMARDs are the next step. These are targeted medicines that block specific parts of the immune system responsible for inflammation.

Some patients worry that because these medicines are so effective, they must be harsher or carry more side effects. This is not true. The side-effect profile of biologic DMARDs is similar to that of conventional medicines. Before starting biologic therapy, your rheumatologist arranges the necessary screening tests to make sure the treatment is safe for you.

What to expect during treatment

Biologic DMARDs are very effective at controlling rheumatoid arthritis. Once the disease is well controlled, your rheumatologist may work to transition you back towards conventional therapy where possible. Throughout treatment, regular monitoring ensures the medicines remain safe and effective.

If your rheumatologist recommends biologic therapy, you should begin it with full confidence after the recommended tests. Started at the right time, these medicines can make a major difference to controlling the disease and protecting your joints.

For more on rheumatoid arthritis treatment options, see our guide to rheumatoid arthritis treatment in Faisalabad.

Frequently asked questions

What are DMARDs?

DMARDs (Disease-Modifying Anti-Rheumatic Drugs) are medicines that slow down rheumatoid arthritis and prevent joint damage, rather than just relieving pain. They are the foundation of modern rheumatoid arthritis treatment.

What is the difference between conventional and biologic DMARDs?

Conventional DMARDs, such as methotrexate, are the first-line treatment and work well for most patients. Biologic DMARDs are newer, targeted medicines used when conventional DMARDs are not enough to control the disease.

Are biologic DMARDs safe?

Yes. The side-effect profile of biologic DMARDs is similar to that of conventional medicines. Before starting them, your rheumatologist carries out screening tests to make sure they are safe for you, and monitors you regularly during treatment.

Are biologic DMARDs available in Pakistan?

Yes. Biologic DMARDs are now readily available in Pakistan, so patients no longer need to travel abroad to access these advanced treatments.

Dr. Naseem Arshad Rheumatologist Faisalabad

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